منابع مشابه
Charting Immune Signaling Proteomes En Route to New Therapeutic Strategies.
The activation state of an antitumor effector T cell in a tumor depends on the sum of all stimulatory signals and inhibitory signals that it receives in the tumor microenvironment. Accumulating data address the increasing complexity of these signals produced by a myriad of immune checkpoint molecules, cytokines, and metabolites. While reductionist experiments have identified key molecules and t...
متن کاملAntigen kinetics determines immune reactivity.
A current paradigm in immunology is that the strength of T cell responses is governed by antigen dose, localization, and costimulatory signals. This study investigates the influence of antigen kinetics on CD8 T cell responses in mice. A fixed cumulative antigen dose was administered by different schedules to produce distinct dose-kinetics. Antigenic stimulation increasing exponentially over day...
متن کاملCorrelation of Tissue Antibodies and Food Immune Reactivity in Randomly Selected Patient Specimens
Copyright: ©2017 Lambert J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Correlation of Tissue Antibodies and Food Immune Reactivity in Randomly Selected Patient Specimens Jama Lambert1* and Aristo V...
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Antibodies against phospholipids (PLa) are often thought to be associated with the development of activated protein C (APC) resistance. In the present study, PLa were followed throughout 29 healthy pregnancies and compared to APC resistance. The level of PLa did not change during pregnancy [6.9 +/- 3.7 GPL week 12 versus 6.3 +/- 2.8 GPL week 37; 3.3 +/- 1.8 MPL versus 3.2 +/- 1.5 MPL; and lupus...
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Heterogeneous cell populations form an interconnected network that determine their collective output. One example of such a heterogeneous immune population is tumor-infiltrating lymphocytes (TILs), whose output can be measured in terms of its reactivity against tumors. While the degree of reactivity varies considerably between different TILs, ranging from null to a potent response, the underlyi...
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ژورنال
عنوان ژورنال: Journal of Food Processing & Technology
سال: 2015
ISSN: 2157-7110
DOI: 10.4172/2157-7110.s1.019